| Abstract | The interaction of 2-amino-4,6-dimethyl pyrimidine (ADMP) with -cyclodextrin (-CD) has been studied by
means of UV absorption, steady state and time resolved fluorescence techniques. Spectral characteristics, bandwidths
and photophysical parameters indicating that ADMP experience two different environments in aqueous solutions:
bulk water and 1:1 (ADMP:-CD) inclusion complexation. The size restriction of the upper rim of -CD partially
include ADMP and prevent the possibility of formation of 1:2 complex. The effective polarity of the cyclodextrin
cavity experienced by the induced ADMP is equivalent with the polarity of an 80:20 methanol–water mixture. |